TUBB1 Rabbit Polyclonal Antibody

CAT#: TA307997

Rabbit Polyclonal antibody to beta Tubulin (tubulin, beta 1)

Product Images

Sample (30 ug whole cell lysate). A:A431. B:Hep G2. 10% SDS PAGE. TA307997 diluted at 1:1000

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  Sample (30 ug of whole cell lysate). A: NIH-3T3. 10% SDS PAGE. TA307997 diluted at 1:1000.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TUBB1 (TA307997) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse (Predicted: Feline)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment contain a sequence corresponding to a region within amino acids 174 and 428 of beta Tubulin (Uniprot ID#Q9H4B7)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 50 kDa
• Gene Name: tubulin beta 1 class VI
• Database Link:
  NP_110400
  Entrez Gene 545486 MouseEntrez Gene 81027 Human
  UniProt ID Q9H4B7
• Background: Microtubules are involved in a wide variety of cellular processes, including mitosis, morphogenesis, platelet formation, and mobility of cilia and flagella. Circulating platelets carry a single marginal microtubule coil that is wound in 8 to 12 turns and is responsible for platelet shape. TUBB1 is the major beta-tubulin expressed in platelets and megakaryocytes and is required for optimal platelet assembly (Wang et al., 1986 [PubMed 3782288]; Schulze et al., 2004 [PubMed 15315966]). [supplied by OMIM]
• Synonyms: beta 1; beta tubulin 1; class VI; dJ543J19.4; OTTHUMP00000031411; tubulin
• Note: Seq homology of immunogen across species: Cat (81%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Gap junction, Pathogenic Escherichia coli infection