MYBPC2 Rabbit Polyclonal Antibody
Frequently bought together (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
USD 200.00
Recombinant protein of human myosin binding protein C, fast type (MYBPC2), 20 µg
USD 867.00
Other products for "MYBPC2"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 1 - 2 ug/mL, ICC: 5 ug/mL |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | MYBPC2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MYBPC2. |
Formulation | PBS containing 0.02% sodium azide. |
Purification | Affinity chromatography purified via peptide column |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | myosin binding protein C, fast type |
Database Link | |
Background | Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the fast-type isoform designated MYBPC2. Both the fast-type and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. MYBPC2 is typically required for strong contractions and functions under anaerobic conditions. It is more similar to the cardiac isoform (MYBPC3) than to the slow-type isoform (MYBPC1) in terms of pCa50-indexed force development, length-independent cooperativity and length dependent activation. It has been suggested that in cardiac and fast muscle MYBPC2 contributes to an internal load, possibly by binding to actin via its N-terminal region. |
Synonyms | MYBPC; MYBPCF |
Reference Data |
Documents
Product Manuals |
FAQs |
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