KCTD15 Rabbit Polyclonal Antibody

CAT#: TA306747

Rabbit Polyclonal KCTD15 Antibody

Product Images

Western blot analysis of KCTD15 in human spleen tissue lysate with KCTD15 antibody at (A) 0.5 and (B) 1 ug/ml.

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  Immunohistochemistry of KCTD15 in human spleen tissue with KCTD15 antibody at 2.5 ug/ml.

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  Immunofluorescence of KCTD15 in human spleen tissue with KCTD15 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: KCTD15 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human KCTD15.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: potassium channel tetramerization domain containing 15
• Database Link:
  NP_001123466
  Entrez Gene 233107 MouseEntrez Gene 499129 RatEntrez Gene 79047 Human
  UniProt ID Q96SI1
• Background: Childhood and adult obesity in the United States and to a lesser extent the rest of the world has increased dramatically over the past decade. Both environmental and genetic factors are involved in the onset and progression of weight gain. Recently, the potassium channel KCTD15 was identified as a genetic loci associated with higher than normal body mass index (BMI) in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Further studies on single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were still significantly associated with higher than normal BMI levels. At least two isoforms of KCTD15 are known to exist.
• Synonyms: MGC2628; MGC25497

Reference Data

• Protein Families: Ion Channels: Other