Neurobeachin (NBEA) Goat Polyclonal Antibody

CAT#: TA302902

Goat Polyclonal Antibody against NBEA

Product Images

TA302902 (1ug/ml) staining of 1) untransfected HEK293T cells 2) HEK293T cells transfected with mouse NBEA. Detected by chemiluminescence. Data kindly provided by Professor John Creemers, K.U. Leuven, Belgium

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  TA302902 (5ug/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:8,000, WB: 1-3ug/mL, IHC: 5-10ug/mL
• Reactivities: Human, Mouse (Expected from sequence similarity: Dog, Cow)
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-DFNRWHYEHQNRY, from the C Terminus of the protein sequence according to NP_056493.3.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: neurobeachin
• Database Link:
  NP_056493
  Entrez Gene 26422 MouseEntrez Gene 477305 DogEntrez Gene 26960 Human
  UniProt ID Q8NFP9
• Background: This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. Alternatively spliced transcript variants may exist, but their full-length nature has not been determined. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
• Synonyms: BCL8B; LYST2