Pafah1b1 Goat Polyclonal Antibody

CAT#: TA302796

Goat Polyclonal Antibody against PAFAH1B1

Product Images

TA302796 staining (2ug/ml) of NIH-3T3 lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1-3µg/ml.
• Reactivities: Human, Rat (Expected from sequence similarity: Mouse, Dog, Pig, Cow)
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence TGSVDQTVKVWECR, from the C Terminus of the protein sequence according to NP_000421.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
• Database Link:
  NP_038653
  Entrez Gene 5048 HumanEntrez Gene 83572 RatEntrez Gene 480656 DogEntrez Gene 18472 Mouse
  UniProt ID P63005
• Background: PAFAH1B1 was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. PAFAH1B1 encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq]
• Synonyms: LIS-1; LIS1; LIS2; MDCR; MDS; PAFAH; PAFAHA