VPS26 (VPS26A) Goat Polyclonal Antibody

CAT#: TA302631

Goat Polyclonal Antibody against VPS26A

Product Images

TA302631 staining (1ug/ml) of Human Kidney lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/4,000. WB: 1-2µg/ml.
• Reactivities: Human (Expected from sequence similarity: Mouse, Rat, Pig, Cow)
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-SPESQASAEQPEM, from the C Terminus of the protein sequence according to NP_004887.2.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 41795 Da
• Gene Name: VPS26 retromer complex component A
• Database Link:
  NP_004887
  Entrez Gene 30930 MouseEntrez Gene 361846 RatEntrez Gene 9559 Human
  UniProt ID O75436
• Background: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Synonyms: HB58; Hbeta58; PEP8A; VPS26