MEF2C Rabbit Polyclonal Antibody

CAT#: TA302220

Rabbit Polyclonal Antibody against MEF2C (S387)

Product Images

MEF2C Antibody (pS387) (Cat. #TA302220) western blot analysis in HL-60, K562 cell line lysates (35ug/lane).This demonstrates the MEF2C antibody detected the MEF2C protein (arrow).

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  Formalin-fixed and paraffin-embedded human brain tissue reacted with MEF2C Antibody (S387) (Cat.#TA302220), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

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  IF image of Hela cell stained with MEF2C Antibody (S387) (Cat#TA302220).Hela cells were incubated with MEF2C primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7 units/ml). Nuclei were counterstained with DAPI (blue).MEF2C immunoreactivity is localized to vesicles and Nucleus significantly.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1:1000, IF: 1:10~50, IHC: 1:10~50
• Reactivities: Human (Predicted: Pig)
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This MEF2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-394 amino acids from human MEF2C.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 51090 Da
• Gene Name: myocyte enhancer factor 2C
• Database Link:
  NP_002388
  Entrez Gene 4208 Human
  UniProt ID Q06413
• Background: MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. This protein controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It may also be involved in neurogenesis and in the development of cortical architecture.
• Synonyms: C5DELq14.3; DEL5q14.3

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: MAPK signaling pathway