Frataxin (FXN) Rabbit Polyclonal Antibody

CAT#: TA302102

Rabbit Polyclonal Antibody against FXN (C-term)

Product Images

Western blot analysis of anti-FXN Antibody (C-term) (Cat#TA302102) in 293 cell line lysates (35ug/lane). FXN (arrow) was detected using the purified Pab.

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  Western blot analysis of FXN (arrow) using rabbit polyclonal FXN Antibody (C-term) (RB12571). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FXN gene (Lane 2) (Origene Technologies).

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  Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with FXN antibody (C-term) (Cat.#TA302102), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:1000, IHC: 1:10~50
• Reactivities: Human (Predicted: Mouse)
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the C-terminal region of human FXN.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 23135 Da
• Gene Name: frataxin
• Database Link:
  NP_000135
  Entrez Gene 14297 MouseEntrez Gene 2395 Human
  UniProt ID Q16595
• Background: FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.
• Synonyms: CyaY; FA; FARR; FRDA; X25

Reference Data

• Protein Families: Druggable Genome