BMAL1 (ARNTL) Rabbit Polyclonal Antibody

CAT#: TA301766

Rabbit Polyclonal Antibody against BMAL

Product Images

Simple Western: BMAL1 Antibody TA301766 - Image shows a specific band for BMAL1 in 0.5 mg/mL of NIH-3T3 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

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  Western Blot: BMAL1 Antibody TA301766 - Detection of BMAL in 3T3/L1 lysates.

Specifications

Product Data

• Applications: ChIP, Simple Western, WB
• Recommended Dilution: Western Blot: 1:100 - 1:200, Simple Western: 1:100, Chromatin Immunoprecipitation (ChIP): 1:10-1:500
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Bacterially expressed human BMAL1
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: aryl hydrocarbon receptor nuclear translocator like
• Database Link:
  NP_001169
  Entrez Gene 406 Human
  UniProt ID O00327
• Background: MOP3 (BMAL1), a general dimerization partner for a subset of the bHLH-PAS (basic-helix-loop-helix-PER-ARNT-SIM) superfamily of transcription regulators, is involved in circadian rhythm generation. MOP3 interacts with MOP4, CLOCK, Hypoxia-inducible factor-1 alpha and -2 alpha. This interaction appears to be distinct from that of the more characterized general partner, ARNT (HIF-1Beta).
• Synonyms: bHLHe5; BMAL1; BMAL1c; JAP3; MOP3; PASD3; TIC

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Circadian rhythm - mammal