SIRT6 Rabbit Polyclonal Antibody

CAT#: TA301523

Rabbit Polyclonal Antibody against SIRT6

Product Images

Simple Western: SIRT6 Antibody TA301523 - Simple Western lane view shows a specific band for SIRT6 in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

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  Western Blot: SIRT6 Antibody TA301523 - Detection of SIRT6 in HeLa whole cell lysate.

Specifications

Product Data

• Applications: Simple Western, WB
• Recommended Dilution: Simple Western: 1:10, Western Blot: 0.5-2 ug/ml
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide made to an internal region of the human SIRT6 protein (within residues 250-350). [Swiss-Prot Q8N6T7]
• Formulation: Tris-citrate/phosphate (pH 7-8) and 0.1% sodium azide
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: sirtuin 6
• Database Link:
  NP_057623
  Entrez Gene 51548 Human
  UniProt ID Q8N6T7
• Background: Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human ageing.
• Synonyms: SIR2L6

Reference Data

• Protein Families: Druggable Genome, Transcription Factors