Calcium Sensing Receptor (CASR) Mouse Monoclonal Antibody [Clone ID: HL 1499]

CAT#: TA301411

Mouse Monoclonal Antibody against Calcium Sensing Receptor (HL 1499)

Product Images

Simple Western: Calcium-sensing R/CaSR Antibody (HL 1499) TA301411 - Image shows a specific band for Calcium Sensing Receptor in 0.5 mg/mL of HEK293 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

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  Western Blot: Calcium-sensing R/CaSR Antibody (HL 1499) TA301411 - Analysis of Calcium Sensing Receptor expression in rat kidney tissue.

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  Western Blot: Calcium-sensing R/CaSR Antibody (HL 1499) TA301411 - Detection of Calcium Sensing Receptor in transfected 293 cell lysate using NB 100-1830. ECL exposure, 5 minutes. In this photo, the protein has aggregated and thus the higher MW band as expected.

Specifications

Product Data

• Clone Name: HL 1499
• Applications: ELISA, FC, IP, Simple Western, WB
• Recommended Dilution: Radioimmunoassay, Simple Western: 1:200, Immunoprecipitation: 5 - 10 ug, Flow Cytometry, Western Blot: 1:50 - 1:200, ELISA: 1:100 - 1:2000
• Reactivities: Human, Mouse, Rabbit, Rat
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: N-tertminal, extracellular region of human Calcium Sensing Receptor (see reference 2).
• Formulation: Tris-glycine, 150mM NaCl and 0.05% sodium azide
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: calcium sensing receptor
• Database Link:
  NP_000379
  Entrez Gene 12374 MouseEntrez Gene 24247 RatEntrez Gene 846 Human
  UniProt ID P41180
• Background: The calcium-sensing receptor (CaSR) is an integral membrane protein that is a member of the G protein-coupled receptor family. It senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.
• Synonyms: CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane