CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: LNK16]

CAT#: SM1073P

CD16 (FCGR3A) mouse monoclonal antibody, clone LNK16, Purified

Specifications

Product Data

• Clone Name: LNK16
• Applications: FC, IP
• Recommended Dilution: Flow Cytometry: Use 10 µl of 1/10-1/20 diluted antibody to label 10e6 cells or 100 µl human whole blood.
  Immunoprecipitation.
  Does not work in Immunohistochemistry on Frozen and Paraffin Sections.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Normal Human peripheral blood granulocytes.
• Specificity: This antibody recognizes CD16.
  This antibody has been reported to block the binding of IgG to the CD16 molecule. (4)
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Ion Exchange Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Fc fragment of IgG receptor IIIa
• Database Link:
  Entrez Gene 2214 Human
  UniProt ID P08637
• Background: CD16 is a 50-65kD cell surface molecule which exists in two forms, a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells.
• Synonyms: FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2