CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: LNK16]

CAT#: SM1073B

CD16 (FCGR3A) mouse monoclonal antibody, clone LNK16, Biotin

Product Images

Staining of human peripheral blood granulocytes with Mouse Anti Human CD16-Biotin.

Specifications

Product Data

• Clone Name: LNK16
• Applications: FC
• Recommended Dilution: Flow Cytometry: Neat-1/5; Use 10µl of the suggested working dilution to label 10e6 cells or 100 µl human whole blood.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Normal human peripheral blood granulocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63.653 myeloma cell line.
• Specificity: This antibody recognises CD16.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% Bovine Serum Albumin as stabilizer.
  Label: Biotin
  State: Liquid purfied IgG fraction.
• Concentration: lot specific
• Purification: Ion Exchange Chromatography
• Conjugation: Biotin
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 2214 Human
  UniProt ID P08637
• Background: CD16 is a 50-65kD cell surface molecule which exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells.
• Synonyms: FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2