PDGF Receptor beta (PDGFRB) Rabbit Polyclonal Antibody
CAT#: AP02728PU-S
PDGF Receptor beta (PDGFRB) rabbit polyclonal antibody, Aff - Purified
Size: 100 ul
Other products for "PDGFRB"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western Blot: 1:500~1:1000. |
Reactivities | Human, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The antiserum was produced against synthesized non-phosphopeptide derived from human PDGF Receptor β around the phosphorylation site of tyrosine 751(V-D-YP-V-P). |
Specificity | PDGF Receptor β antibody detects endogenous levels of total PDGF Receptor β protein. |
Formulation | PBS (without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl, 0.02% sodium azide and 50% glycerol. State: Aff - Purified State: Liquid purified IgG |
Concentration | lot specific |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Conjugation | Unconjugated |
Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | platelet derived growth factor receptor beta |
Database Link | |
Background | Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons. |
Synonyms | PDGF-R-beta, PDGF Receptor beta |
Reference Data |
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