CD51 (ITGAV) Mouse Monoclonal Antibody [Clone ID: 13C2]

CAT#: AM08161FC-N

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CD51 (ITGAV) mouse monoclonal antibody, clone 13C2, FITC



USD 359.00


Availability*
3 Days

Size
    • 100 Tests


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Specifications

Product Data
Clone Name 13C2
Applications FC
Recommended Dilution Flow Cytometry: 10 µL/10e6 cells.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity This antibody recognizes CD51.
Formulation PBS containing 0.09% Sodium Azide as preservative.
Label: FITC
State: Liquid purified Ig fraction.
Label: Fluorescein Isothiocyanate Isomer 1
Conjugation FITC
Storage Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name integrin subunit alpha V
Background Integrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, and platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, and beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment and spreading on vitronectin and other matrix components. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Alpha-V/beta-6 binds to foot-and-mouth disease virus (FMDV) VP1 protein and acts as a receptor for this virus By similarity. Alpha-V/beta-6 binds to coxsackievirus A9 and coxsackievirus B1 capsid proteins and acts as a receptor for these viruses.
It also mediates leukocyte-endothelial cell adhesion via interaction with CD31. (Ref.1-4)
Synonyms Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha
Reference Data
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