CD69 Mouse Monoclonal Antibody [Clone ID: FN50]

CAT#: AM03132FC-N

CD69 mouse monoclonal antibody, clone FN50, FITC

Product Images

Surface staining of human peripheral blood using anti-CD69 antibody (clone FN50) after overnight activation of T cells by anti-CD3 (clone MEM-57).

Specifications

Product Data

• Clone Name: FN50
• Applications: FC
• Recommended Dilution: Flow Cytometry analysis of human blood cells using 20 ml reagent / 100 ml of whole blood or 10e6 cells in a suspension.
  The content of a vial (2 ml) is sufficient for 100 tests.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Anti-µ-stimulated human B lymphocytes
• Specificity: The antibody recognizes CD69, an lymphocyte early activation marker detected as a 53 kDa band under nonreducing and as 29 + 32 kDa double band under reducing SDS-PAGE conditions.
• Formulation: PBS containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
  Label: FITC
  State: Liquid purified Ig fraction
  Label: Conjugated with Fluorescein isothiocyanate under optimum conditions. The reagent is free of unconjugated and adjusted for direct use. No reconstitution is necessary
• Conjugation: FITC
• Storage: Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: CD69 molecule
• Database Link:
  Entrez Gene 969 Human
  UniProt ID Q07108
• Background: CD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets; it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy.
• Synonyms: GP32/28, Leu-23, MLR-3, EA1, BL-AC/P26, AIM