IGFBP3 (NM_001013398) Human Recombinant Protein

CAT#: TP762601

Purified recombinant protein of Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein IGFBP3 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of IGFBP3
• Tag: N-GST and C-HIS
• Predicted MW: 32.21 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001013416
• Locus ID: 3486
• UniProt ID: P17936
• Cytogenetics: 7p12.3
• Refseq Size: 2638
• Refseq ORF: 891
• Synonyms: BP-53; IBP3
• Summary: This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: p53 signaling pathway