NRG1 (NM_013964) Human Recombinant Protein
CAT#: TP762500
Purified recombinant protein of Human neuregulin 1 (NRG1), transcript variant HRG-alpha, 20Ser-230Gln, with N-terminal His tag, expressed in E.coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region (20Ser-230Gln) of NRG1
|
Tag | N-His |
Predicted MW | 24.9kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_039258 |
Locus ID | 3084 |
UniProt ID | Q02297, Q6PK61 |
Cytogenetics | 8p12 |
Refseq Size | 2224 |
Refseq ORF | 1920 |
Synonyms | ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; NRG1-IT2; SMDF |
Summary | The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016] |
Protein Families | Druggable Genome, Secreted Protein, Transcription Factors, Transmembrane |
Protein Pathways | ErbB signaling pathway |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC415553 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 206.00 |
|
LC415555 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC415558 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC415560 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 206.00 |
|
LC431269 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC431507 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC431526 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY415553 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant HRG-beta1 |
USD 665.00 |
|
LY415555 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant HRG-beta3 |
USD 436.00 |
|
LY415558 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant GGF |
USD 436.00 |
|
LY415560 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant HRG-alpha |
USD 665.00 |
|
LY431269 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant ndf43c |
USD 436.00 |
|
LY431507 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant HRG-beta1d |
USD 436.00 |
|
LY431526 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant HRG-beta1c |
USD 436.00 |
|
TP721214 | Purified recombinant protein of Human neuregulin 1 (NRG1), transcript variant GGF2 |
USD 330.00 |
|
TP721215 | Purified recombinant protein of Human neuregulin 1 (NRG1), transcript variant GGF2 |
USD 330.00 |
|
TP762321 | Purified recombinant protein of Human neuregulin 1 (NRG1), transcript variant HRG-beta1, Ser20-Glu242, with N-terminal His tag, expressed in E.coli, 50ug |
USD 249.00 |
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