EPX (NM_000502) Human Recombinant Protein

CAT#: TP762293

Purified recombinant protein of Human eosinophil peroxidase (EPX), Arg140-Met422, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein EPX was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Arg140-Met422) of EPX
• Tag: N-His
• Predicted MW: 32.5 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000493
• Locus ID: 8288
• UniProt ID: P11678
• Cytogenetics: 17q22
• Refseq Size: 2731
• Refseq ORF: 2145
• Synonyms: EPO; EPP; EPX-PEN; EPXD
• Summary: This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency. [provided by RefSeq, Feb 2016]
• Protein Families: Druggable Genome
• Protein Pathways: Asthma