KCNH2 (NM_000238) Human Recombinant Protein

CAT#: TP762261

Purified recombinant protein of Human potassium voltage-gated channel, subfamily H (eag-related), member 2 (KCNH2), transcript variant 1, Met1-Pro298, with N-terminal His tag, expressed in E.coli, 50ug


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USD 249.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Met1-Pro298) of KCNH2
Tag N-His
Predicted MW 31.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000229
Locus ID 3757
UniProt ID Q12809, A0A090N8Q0, Q15BH2
Cytogenetics 7q36.1
Refseq Size 3900
Refseq ORF 3477
Synonyms ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1
Summary This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Ion Channels: Potassium, Transcription Factors, Transmembrane

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