TIMP3 (NM_000362) Human Recombinant Protein

CAT#: TP762069

Purified recombinant protein of Human TIMP metallopeptidase inhibitor 3 (TIMP3),Cys24-End, with N-terminal His tag, expressed in E. coli, 50ug


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USD 261.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Cys24-End) of TIMP3
Tag N-His
Predicted MW 21.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000353
Locus ID 7078
UniProt ID P35625
Cytogenetics 22q12.3
Refseq Size 5496
Refseq ORF 633
Synonyms HSMRK222; K222; K222TA2; SFD
Summary This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein

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