CDC42 binding protein kinase alpha (CDC42BPA) (NM_014826) Human Recombinant Protein

CAT#: TP761915

Purified recombinant protein of Human CDC42 binding protein kinase alpha (DMPK-like) (CDC42BPA), transcript variant A, Ser1419-Pro1638, with N-terminal HIS tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Ser1419-Pro1638) of CDC42BPA
• Tag: N-His
• Predicted MW: 30 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_055641
• Locus ID: 8476
• UniProt ID: Q5VT25
• Cytogenetics: 1q42.13
• Refseq Size: 7776
• Refseq ORF: 5262
• Synonyms: MRCK; MRCKA; PK428
• Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2018]
• Protein Families: Druggable Genome, Protein Kinase