Activin A Receptor Type IB(ACVR1B) (NM_004302) Human Recombinant Protein

CAT#: TP761428

Purified recombinant protein of Human activin A receptor, type IB (ACVR1B), transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug


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USD 205.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human activin A receptor, type IB (ACVR1B), transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Species Human
Expression Host E.Coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding human full-length ACVR1B
Tag N-GST and C-His
Predicted MW 84.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris,pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl.
Reference Data
RefSeq NP_004293
Locus ID 91
Refseq Size 4540
Cytogenetics 12q13.13
Refseq ORF 1515
Synonyms ACTRIB; ACVRLK4; ALK4; SKR2
Summary This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
Protein Families Protein Kinase, Transmembrane, Druggable Genome
Protein Pathways MAPK signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, TGF-beta signaling pathway, Adherens junction, Pathways in cancer, Colorectal cancer, Pancreatic cancer, Chronic myeloid leukemia

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Anti-ACVR1B rabbit polyclonal antibody
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