MITF (NM_198158) Human Recombinant Protein

CAT#: TP761396

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Purified recombinant protein of Human microphthalmia-associated transcription factor (MITF), transcript variant 5, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug


 Product Datasheet for 'TP761396'

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USD 205.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human microphthalmia-associated transcription factor (MITF), transcript variant 5, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Species Human
Expression Host E. coli
Tag N-GST and C-His
Predicted MW 74.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris,pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl.
Reference Data
RefSeq NP_937801
Locus ID 4286
Refseq Size 4454
Cytogenetics 3p13
Refseq ORF 1239
Synonyms bHLHe32; CMM8; COMMAD; MI; WS2; WS2A
Summary The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Melanogenesis, Melanoma, Pathways in cancer

Citations (1)

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