MITF (NM_198158) Human Recombinant Protein
Purified recombinant protein of Human microphthalmia-associated transcription factor (MITF), transcript variant 5, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Product Datasheet for 'TP761396'
Specifications
Product Data | |
Description | Purified recombinant protein of Human microphthalmia-associated transcription factor (MITF), transcript variant 5, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug |
Species | Human |
Expression Host | E. coli |
Tag | N-GST and C-His |
Predicted MW | 74.1 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris,pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl. |
Reference Data | |
RefSeq | NP_937801 |
Locus ID | 4286 |
Refseq Size | 4454 |
Cytogenetics | 3p13 |
Refseq ORF | 1239 |
Synonyms | bHLHe32; CMM8; COMMAD; MI; WS2; WS2A |
Summary | The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017] |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Melanogenesis, Melanoma, Pathways in cancer |
Citations (1)
The use of this Proteins has been cited in the following citations: |
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Detecting transcription factors with allosteric DNA-Silver nanocluster switches
,Li, B;Chen, Y;Wang, J;Lu, Q;Zhu, W;Luo, J;Hong, J;Zhou, X;,
Analytica Chimica Acta 2018
[MITF]
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LY424990 | Transient overexpression lysate of microphthalmia-associated transcription factor (MITF), transcript variant 4 |
USD 315.00 |
|
LY404984 | Transient overexpression lysate of microphthalmia-associated transcription factor (MITF), transcript variant 6 |
USD 495.00 |
|
LC424990 | MITF HEK293T cell transient overexpression lysate (as WB positive control) |
USD 95.00 |
|
TP761494 | Purified recombinant protein of Human microphthalmia-associated transcription factor (MITF), transcript variant 4, full length, with N-terminal HIS tag, expressed in E.coli, 50ug |
USD 205.00 |
|
LC404987 | MITF HEK293T cell transient overexpression lysate (as WB positive control) |
USD 55.00 |
|
LC404984 | MITF HEK293T cell transient overexpression lysate (as WB positive control) |
USD 155.00 |
|
LC416461 | Transient overexpression lysate of microphthalmia-associated transcription factor (MITF), transcript variant 3 |
USD 55.00 |
USD 335.00