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DDIT3 (NM_004083) Human Recombinant Protein

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SKU
TP761307
Purified recombinant protein of Human DNA-damage-inducible transcript 3 (DDIT3), transcript variant 5, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length DDIT3
Tag N-GST and C-His
Predicted MW 45 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_004074
Locus ID 1649
UniProt ID P35638
Cytogenetics 12q13.3
RefSeq Size 924
RefSeq ORF 507
Synonyms AltDDIT3; C/EBPzeta; CEBPZ; CHOP; CHOP-10; CHOP10; GADD153
Summary This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. provided by RefSeq, Aug 2010
Protein Categories Cancer: Sarcoma, Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Transcription Factors
Protein Pathways MAPK signaling pathway
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Other "DDIT3" proteins (4)
SKU Description Size Price
LC418226 Lyophilized DDIT3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC434039 Lyophilized DDIT3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418226 Transient overexpression lysate of DNA-damage-inducible transcript 3 (DDIT3) (as WB positive control) 100 ug
$436.00
LY434039 Transient overexpression lysate of DNA-damage-inducible transcript 3 (DDIT3), transcript variant 1 (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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