POLDIP1 (KCTD13) (NM_178863) Human Recombinant Protein

CAT#: TP760326

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Purified recombinant protein of Homo sapiens potassium channel tetramerisation domain containing 13 (KCTD13), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug



  View other "KCTD13" proteins (3)

USD 215.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Homo sapiens potassium channel tetramerisation domain containing 13 (KCTD13), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding human full-length KCTD13
Tag N-His
Predicted MW 36.2 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_849194
Locus ID 253980
Refseq Size 1745
Cytogenetics 16p11.2
Refseq ORF 987
Synonyms BACURD1; FKSG86; hBACURD1; PDIP1; POLDIP1
Summary Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:19782033). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome (PubMed:19782033) Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission. [UniProtKB/Swiss-Prot Function]
Protein Families Ion Channels: Other, Transcription Factors

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