Cardiac Troponin T (TNNT2) (NM_000364) Human Recombinant Protein

CAT#: TP750172

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Purified recombinant protein of Human troponin T type 2 (cardiac) (TNNT2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50 ug



  View other "TNNT2" proteins (16)

USD 215.00


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2 Weeks

Size
    • 50 ug


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Specifications

Product Data
Description Purified recombinant protein of Human troponin T type 2 (cardiac) (TNNT2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50 ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding the full-length of TNNT2
Tag N-HIS
Predicted MW 35.4KDa
Concentration >50 ug/mL as determined by spectrophotometrically(A280) method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from 0.01 M HCl,reconstitute with Tris/urea buffer (20 mM Tris pH7.5, 7 M urea, 5 mM EDTA, 15 mM β- mercaptoethanol).
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000355
Locus ID 7139
Refseq Size 1153
Cytogenetics 1q32.1
Refseq ORF 885
Synonyms CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC
Summary The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

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