Ki67 (MKI67) Human Recombinant Protein

CAT#: TP727649

Recombinant Human Ki67/MKI67 (N-GST)

Specifications

Product Data

• Species: Human
• Protein Source: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Met1-Pro120
• Tag: N-GST
• Buffer: Lyophilized from a 0.2 um filtered solution of PBS,pH7.4.
• Note: Recombinant Human Proliferation Marker Protein Ki-67 is produced by our E.coli expression system and the target gene encoding Met1-Pro120 is expressed with a GST tag at the N-terminus.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 4288
• UniProt ID: P46013
• Summary: MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferation. MKI67 is contextually expressed, being potentially found in all cells that are not in the Go phase of the cell cycle. Thus, MKI67 qualifies as a cell proliferation marker. It is also associated with ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition of ribosomal RNA synthesis.