Csf3 Mouse Recombinant Protein
CAT#: TP727053
Recombinant Mouse Granulocyte Colony-Stimulating Factor/G-CSF/CSF3(C-6His)
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Specifications
Product Data | |
Species | Mouse |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Val31-Ala208
|
Tag | C-His |
Buffer | Lyophilized from a 0.2 um filtered solution of 10mM Sodium Citrate,0.1% Tween 20, pH3.5. |
Note | Recombinant Mouse Granulocyte Colony-Stimulating Factor is produced by our Mammalian expression system and the target gene encoding Val31-Ala208 is expressed with a 6His tag at the C-terminus. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 12985 |
UniProt ID | P09920 |
Summary | Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of alpha-helical motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. G-CSF is a cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent. |
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