Cd79b Mouse Recombinant Protein
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Specifications
Product Data | |
Species | Mouse |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Val26-Asp158
|
Tag | C-Fc |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS,pH7.4. |
Note | Recombinant Mouse CD79B is produced by our Mammalian expression system and the target gene encoding Val26-Asp158 is expressed with a Fc tag at the C-terminus. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 15985 |
UniProt ID | P15530 |
Summary | CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation. |
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