Mouse Recombinant Protein

CAT#: TP724726

Recombinant Mouse SIGLEC-15 (C-His)

Specifications

Product Data

• Species: Mouse
• Protein Source: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Arg24-Thr262
• Tag: C-His
• Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Note: Recombinant Mouse SIGLEC-15 (C-His) is produced by Human Cells. The target gene encoding Arg24-Thr262 is expressed with a C-His tag.
• Stability: 12 months from date of despatch

Reference Data

• Summary: Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.