Il12b Mouse Recombinant Protein

CAT#: TP724642

Recombinant Mouse Interleukin-12/IL-12 (C-His)

Specifications

Product Data

• Species: Mouse
• Protein Source: Human 293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  M23-S335; R23-A125
• Tag: C-8His
• Buffer: Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
• Note: Recombinant Mouse Interleukin-12 is produced by Human 293 Cells. The target gene encoding M23-S335; R23-A125 is expressed with a 8His tag at the C terminus.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 16160
• UniProt ID: P43432
• Summary: Interleukin-12 (IL-12) is a heterodimeric pleiotropic cytokine that consists of IL12A (p35) and IL12B (p40) subunits. IL?12 is expressed by macrophages and B lymphocytes and act as a growth factor for activated T and NK cells, help enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Studies have shown that IL?12 is a key mediator of cellular-immunity and induces the differentiation of Th1 cells from precursor T helper cells. Based on its activities, it has been predicted that IL?12 may have therapeutic potential as a vaccine adjuvant that promotes cellular-immunity and as an anti-tumor and anti-viral agent.