BLK (NM_001715) Human Recombinant Protein

CAT#: TP720911XL

Purified recombinant protein of Human B lymphoid tyrosine kinase (BLK)

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Gly2-Pro505
• Tag: C-His
• Predicted MW: 58.7 kDa
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at -80°C.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_001706
• Locus ID: 640
• UniProt ID: P51451, Q05D26
• Cytogenetics: 8p23.1
• Refseq Size: 2215
• Refseq ORF: 1515
• Synonyms: MODY11
• Summary: This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010]
• Protein Families: Druggable Genome, Protein Kinase