ATG4A (NM_178270) Human Recombinant Protein

CAT#: TP720907L

Purified recombinant protein of Human ATG4 autophagy related 4 homolog A (S. cerevisiae) (ATG4A), transcript variant 2

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Met1-Val398
• Tag: N-His
• Predicted MW: 47.5 kDa
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at -80°C.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_840054
• Locus ID: 115201
• UniProt ID: Q8WYN0
• Cytogenetics: Xq22.3
• Refseq Size: 2117
• Refseq ORF: 1008
• Synonyms: APG4A; AUTL2
• Summary: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. [provided by RefSeq, Mar 2016]
• Protein Families: Protease
• Protein Pathways: Regulation of autophagy