Semenogelin I (SEMG1) (NM_198139) Human Recombinant Protein

CAT#: TP720700

Purified recombinant protein of Human semenogelin I (SEMG1), transcript variant 2

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Gln24-Thr402
• Tag: C-His
• Predicted MW: 43.8 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage: Store at -80°C.
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_937782
• Locus ID: 6406
• UniProt ID: P04279
• Cytogenetics: 20q13.12
• Refseq Size: 1469
• Refseq ORF: 1206
• Synonyms: CT103; MGC14719; RATSVPIIA; semenogelin I; SEMG; seminal vesicle protein, secretion 2; seminal vesicle secretory protein 2; SGI; SVPIIA; Svs2; Svs2p2
• Summary: The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. This preproprotein is proteolytically processed by the prostate-specific antigen (PSA) protease to generate multiple peptide products that exhibit distinct functions. One of these peptides, SgI-29, is an antimicrobial peptide with antibacterial activity. This proteolysis process also breaks down the gel matrix and allows the spermatozoa to move more freely. This gene and another similar semenogelin gene are present in a gene cluster on chromosome 20. [provided by RefSeq, Feb 2016]
• Protein Families: Secreted Protein