DYNLL1 (NM_001037494) Human Recombinant Protein
CAT#: TP720193
Recombinant protein of human dynein, light chain, LC8-type 1 (DYNLL1), transcript variant 1
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Gly89
|
Tag | N-His |
Predicted MW | 12.5 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_001032583 |
Locus ID | 8655 |
UniProt ID | P63167, Q6FGH9 |
Cytogenetics | 12q24.31 |
Synonyms | DLC1; DLC8; DNCL1; DNCLC1; hdlc1; LC8; LC8a; PIN |
Summary | Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC418456 | DYNLL1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC421911 | DYNLL1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC421912 | DYNLL1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY418456 | Transient overexpression lysate of dynein, light chain, LC8-type 1 (DYNLL1), transcript variant 3 |
USD 436.00 |
|
LY421911 | Transient overexpression lysate of dynein, light chain, LC8-type 1 (DYNLL1), transcript variant 1 |
USD 436.00 |
|
LY421912 | Transient overexpression lysate of dynein, light chain, LC8-type 1 (DYNLL1), transcript variant 2 |
USD 436.00 |
|
PH318700 | DYNLL1 MS Standard C13 and N15-labeled recombinant protein (NP_001032584) |
USD 3,255.00 |
|
PH318752 | DYNLL1 MS Standard C13 and N15-labeled recombinant protein (NP_003737) |
USD 3,255.00 |
|
PH319822 | DYNLL1 MS Standard C13 and N15-labeled recombinant protein (NP_001032583) |
USD 3,255.00 |
|
TP318700 | Recombinant protein of human dynein, light chain, LC8-type 1 (DYNLL1), transcript variant 2, 20 µg |
USD 867.00 |
|
TP318752 | Recombinant protein of human dynein, light chain, LC8-type 1 (DYNLL1), transcript variant 3, 20 µg |
USD 867.00 |
|
TP319822 | Recombinant protein of human dynein, light chain, LC8-type 1 (DYNLL1), transcript variant 1, 20 µg |
USD 867.00 |
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