MCSF Receptor (CSF1R) (NM_005211) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | Sf9 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-DDK |
| Predicted MW | 55.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_005202 |
| Locus ID | 1436 |
| UniProt ID | P07333 |
| Cytogenetics | 5q32 |
| RefSeq Size | 3985 |
| RefSeq ORF | 2916 |
| Synonyms | BANDDOS; C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R |
| Summary | The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. provided by RefSeq, Mar 2017 |
| Protein Categories | Cancer: Gynecologic, CD Markers, Chemokines, Cytokines, Enzyme: Kinases, Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Pathways in cancer |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "MCSF Receptor" proteins (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH305288 | CSF1R MS Standard C13 and N15-labeled recombinant protein (NP_005202) | 10 ug |
$3,360.00
|
|
| LC401594 | Lyophilized CSF1R HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401594 | Transient overexpression lysate of colony stimulating factor 1 receptor (CSF1R) (as WB positive control) | 100 ug |
$436.00
|
|
| TP305288 | Recombinant protein of human colony stimulating factor 1 receptor (CSF1R), 20 µg | 20 ug |
$737.00
|
|
| TP700112 | Purified recombinant protein of human colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog (CSF1R), with C-terminal DDK/His tag, expressed in human cells, 20 µg | 20 ug |
$900.00
|
|
| TP723975 | Recombinant human CSF1R protein with C-terminal 6×His tag | 100 ug |
$770.00
|
|
Citations
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