MCSF Receptor (CSF1R) (NM_005211) Human Recombinant Protein

SKU
TP710105
Recombinant protein of human colony stimulating factor 1 receptor (CSF1R), residues 20-517aa, with C-terminal DDK tag, expressed in sf9, 20ug
  $540.00
In Stock*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC205288, encoding the region(Met-Ile20-Pro517) of Homo sapiens CSF1R
Tag C-DDK
Predicted MW 55.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_005202
Locus ID 1436
UniProt ID P07333
Cytogenetics 5q32
RefSeq Size 3985
RefSeq ORF 2916
Synonyms BANDDOS; C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R
Summary The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. provided by RefSeq, Mar 2017
Protein Categories Cancer: Gynecologic, CD Markers, Chemokines, Cytokines, Enzyme: Kinases, Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Pathways in cancer
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other "MCSF Receptor" proteins (6)
SKU Description Size Price
PH305288 CSF1R MS Standard C13 and N15-labeled recombinant protein (NP_005202) 10 ug
$3,360.00
LC401594 Lyophilized CSF1R HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401594 Transient overexpression lysate of colony stimulating factor 1 receptor (CSF1R) (as WB positive control) 100 ug
$436.00
TP305288 Recombinant protein of human colony stimulating factor 1 receptor (CSF1R), 20 µg 20 ug
$737.00
TP700112 Purified recombinant protein of human colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog (CSF1R), with C-terminal DDK/His tag, expressed in human cells, 20 µg 20 ug
$900.00
TP723975 Recombinant human CSF1R protein with C-terminal 6×His tag 100 ug
$770.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products