AMPD1 (NM_000036) Human Recombinant Protein

CAT#: TP701250

Purified recombinant protein of Human adenosine monophosphate deaminase 1 (AMPD1), transcript variant 1, mutant（K320I）, 20ug

Product Images

Coomassie blue staining of purified AMPD1 protein (Cat #TP701250). The protein was produced from mammalian cells transfected with AMPD1 cDNA clone (Cat #RC217919).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, RC217919, encoding the full-length of AMPD1(K320I)
• Tag: C-Myc/DDK
• Predicted MW: 86.5 kDa
• Concentration: >0.05 µg/µL as determined by microplate Bradford method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000027
• Locus ID: 270
• UniProt ID: P23109
• Cytogenetics: 1p13.2
• Refseq Size: 2426
• Refseq ORF: 2241
• Synonyms: MAD; MADA; MMDD
• Summary: Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Purine metabolism