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Whamm (NM_001004185) Mouse Recombinant Protein

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SKU
TP523421
Purified recombinant protein of Mouse WAS protein homolog associated with actin, golgi membranes and microtubules (Whamm), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Size:
20 ug
  $1,020.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>Peptide sequence encoded by MR223421
Blue=ORF Red=Cloning site Green=Tag(s)

MDSEQPDSLDGWVPLREDLFPEPERHQLRFLVAWNAAKGQFAVTCHDRTAQRRRRERREAGDGGCSWAG
VLSPAGFRGAHRQLAALWPALEPCFPPLPPELDAASGAGWGLGRGLWALLWPLLWPAPADPGDSALQEL
CRQLEHYLGLAAEGCGGATVRDVLFPAPGDSADCEGLSEFRERTLRARLGQTATRLHQVLQDHGKANTM
VALMKVYQEEDELYQELVTMATTFFQYLLQPFRDMREVATSCKLGILKSLDEDELGPRRVAALQKEASE
WTRQAEEAVGSIQDITVNYFKETVTALTGMQKQMEQDQKRFGQAAWATAMPRLENLKLMLARETLQLMR
AKELCLKHRQAEIQRKVEDLPRQGKQLDVVDELEIQCYEIQLELYDVKLEMLRNEETILVTRLDSVKRL
ITEKQAEVIYYDPCESPEELQSLAPDLELHLGDNRELRALSQQCQRLEAQRGRICSRRALLRNRKDHCR
ENHQLRLQQAKQSLRHLHQHHSIQMKRDKVKEEEQKKKEWIDHERQKTLERLRAYKEKCPAHRSALKTT
CSESMVSNLPGGRSQKRLSTAHHHKTAHPASSKTGSAVPLPEASVRPPEHQDPCGSVPVQAFVPVSDQT
LSGSSEDLSLPPQPPAPPLPPPPPPPPPPPLPPALSSFQGTTHQNLGLRTLATEDRPLPLACDPSAGRP
CDYQGPGSMDEVLASLRQGKASLRKVETPTLPHPGTSVNEQVLAAIRQGVQLKKVHTGQGVDPGKKSTS
DLERSIREALERIKKVSADSEEDNDEPSPTEWDR
TRTRPLEQKLISEEDLAANDILDYKDDDDKV

Recombinant protein using MR223421 also available, TP523421
Tag C-MYC/DDK
Predicted MW 89.4 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001004185
Locus ID 434204
UniProt ID Q571B6
Cytogenetics 7 D3
RefSeq Size 3069
RefSeq ORF 2379
Synonyms BB081391; mKIAA1971; Whdc1
Summary Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes. Involved as a regulator of Golgi positioning and morphology. Its activity in membrane tubulation requires F-actin and interaction with microtubules. Proposed to use coordinated actin-nucleating and microtubule-binding activities of distinct WHAMM molecules to drive membrane tubule elongation; when MT-bound can recruit and remodel membrane vesicles but is prevented to activate the Arp2/3 complex. Required for RhoD-dependent actin reorganization such as in cell adhesion and cell migration (By similarity). Participates in vesicle transport between the reticulum endoplasmic and the Golgi complex.UniProtKB/Swiss-Prot Function
Protein Categories Growth Factors, Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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