PRMT4 (CARM1) (NM_199141) Human Recombinant Protein
SKU
TP317483
Recombinant protein of human coactivator-associated arginine methyltransferase 1 (CARM1), 20 µg
$737.00
4 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 65.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_954592 |
| Locus ID | 10498 |
| UniProt ID | Q86X55 |
| Cytogenetics | 19p13.2 |
| RefSeq Size | 2968 |
| RefSeq ORF | 1836 |
| Synonyms | PRMT4 |
| Summary | This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9. provided by RefSeq, Aug 2013 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PRMT4" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH317483 | CARM1 MS Standard C13 and N15-labeled recombinant protein (NP_954592) | 10 ug |
$3,360.00
|
|
| LC404751 | Lyophilized CARM1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY404751 | Transient overexpression lysate of coactivator-associated arginine methyltransferase 1 (CARM1) (as WB positive control) | 100 ug |
$665.00
|
|
Citations
Inhibition of CARM1-Mediated Methylation of ACSL4 Promotes Ferroptosis in Colorectal Cancer
Feng, Rao, Zhang et al
Adv Sci (Weinh) (2023)
Feng, Rao, Zhang et al
Adv Sci (Weinh) (2023)
Cited by 48
AI Summary: OriGene’s CARM1 protein (TP317483) was used in this study to investigate the interaction and methylation of ACSL4, helping to elucidate the molecular mechanisms by which CARM1 regulates ferroptosis in colorectal cancer.
Snippet: The proteins for CARM1 (OriGene, TP317483) and ACSL4 (H00002182-P01, Abnova) were commercially available. The CARM1 protein was incubated with GST or GST-ACSL4 fusion proteins bound to glutathione Sepharose beads at 4 °C overnight. GST and GST fusion proteins were boiled, subjected to SDS-PAGE, and verified by Coomassie Blue staining. Binding proteins were detected by Western blotting
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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