Ribonuclease Inhibitor (RNH1) (NM_203387) Human Recombinant Protein

CAT#: TP313642

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Recombinant protein of human ribonuclease/angiogenin inhibitor 1 (RNH1), transcript variant 6


Product Datasheet for 'TP313642'


  View other "RNH1" proteins (35)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human ribonuclease/angiogenin inhibitor 1 (RNH1), transcript variant 6
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC213642. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 49.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_976321
Locus ID 6050
Refseq Size 2015
Cytogenetics 11p15.5
Refseq ORF 1383
Synonyms RAI; RNH
Summary Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo. [supplied by OMIM, Jul 2010]

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