Ribonuclease Inhibitor (RNH1) (NM_203389) Human Mass Spec Standard

CAT#: PH319235

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RNH1 MS Standard C13 and N15-labeled recombinant protein (NP_976323)

  View other "RNH1" proteins (29)

USD 2,260.00

3 Weeks

    • 10 ug

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Product Data
Description RNH1 MS Standard C13 and N15-labeled recombinant protein (NP_976323)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219235
Predicted MW 50 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_976323
RefSeq Size 1842
RefSeq ORF 1383
Synonyms RAI; RNH
Locus ID 6050
UniProt ID P13489, A0A140VJT8
Cytogenetics 11p15.5
Summary Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010]


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