Plasma Kallikrein 1B (KLKB1) (NM_000892) Human Recombinant Protein

CAT#: TP311985

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Recombinant protein of human kallikrein B, plasma (Fletcher factor) 1 (KLKB1)



  View other "KLKB1" proteins (3)

USD 788.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human kallikrein B, plasma (Fletcher factor) 1 (KLKB1)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC211985. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 41.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000883
Locus ID 3818
Refseq Size 2245
Cytogenetics 4q35.2
Refseq ORF 1914
Synonyms KLK3; PKK; PKKD; PPK
Summary This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Protein Families Druggable Genome, Protease
Protein Pathways Complement and coagulation cascades

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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