HES1 (NM_005524) Human Recombinant Protein

CAT#: TP311709

Recombinant protein of human hairy and enhancer of split 1, (Drosophila) (HES1)

Product images

Specifications

Product Data

• Description: Recombinant protein of human hairy and enhancer of split 1, (Drosophila) (HES1)
• Species: Human
• Expression Host: HEK293T
• Tag: C-Myc/DDK
• Predicted MW: 29.4 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Reference Data

• RefSeq: NP_005515
• Locus ID: 3280
• Refseq Size: 1471
• Cytogenetics: 3q29
• Refseq ORF: 840
• Synonyms: bHLHb39; HES-1; HHL; HRY
• Summary: This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. [provided by RefSeq, Jul 2008]
• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transcription Factors
• Protein Pathways: Maturity onset diabetes of the young, Notch signaling pathway