ATP6V1F (NM_004231) Human Recombinant Protein

CAT#: TP310728

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Recombinant protein of human ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F (ATP6V1F)


 Product Datasheet for 'TP310728'

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USD 748.00


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    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F (ATP6V1F)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 13.2 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_004222
Locus ID 9296
Refseq Size 748
Cytogenetics 7q32.1
Refseq ORF 357
Synonyms ATP6S14; VATF; Vma7
Summary This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein. [provided by RefSeq, Jul 2008]
Protein Pathways Epithelial cell signaling in Helicobacter pylori infection, Metabolic pathways, Oxidative phosphorylation, Vibrio cholerae infection

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