Phosphatidic acid phosphatase type 2B (PLPP3) (NM_003713) Human Recombinant Protein

CAT#: TP303480

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Recombinant protein of human phosphatidic acid phosphatase type 2B (PPAP2B), transcript variant 1


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    • 20 ug


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Product Data
Description Recombinant protein of human phosphatidic acid phosphatase type 2B (PPAP2B), transcript variant 1
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 34.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_003704
Locus ID 8613
Refseq Size 3324
Cytogenetics 1p32.2
Refseq ORF 933
Synonyms Dri42; LPP3; PAP2B; PPAP2B; VCIP
Summary The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells. [provided by RefSeq, Mar 2010]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Ether lipid metabolism, Fc gamma R-mediated phagocytosis, Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, Sphingolipid metabolism

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