FMO2 (NM_001460) Human Recombinant Protein

CAT#: TP303237

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Recombinant protein of human flavin containing monooxygenase 2 (non-functional) (FMO2)


 Product Datasheet for 'TP303237'

  View other "FMO2" proteins (3)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human flavin containing monooxygenase 2 (non-functional) (FMO2)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 53.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001451
Locus ID 2327
Refseq Size 5304
Cytogenetics 1q24.3
Refseq ORF 1413
Synonyms FMO1B1
Summary This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
Protein Pathways Drug metabolism - cytochrome P450

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