UGP2 (NM_001001521) Human Recombinant Protein

CAT#: TP300246

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Recombinant protein of human UDP-glucose pyrophosphorylase 2 (UGP2), transcript variant 2


 Product Datasheet for 'TP300246'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human UDP-glucose pyrophosphorylase 2 (UGP2), transcript variant 2
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 55.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001001521
Locus ID 7360
Refseq Size 2129
Cytogenetics 2p15
Refseq ORF 1491
Synonyms pHC379; UDPG; UDPGP; UDPGP2; UGP1; UGPP1; UGPP2
Summary The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways, Pentose and glucuronate interconversions, Starch and sucrose metabolism

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