Myostatin (His-tagged Fusion Protein) Human Protein

CAT#: PA512X

Myostatin (His-tagged Fusion Protein) human protein, 0.1 mg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDPSSRSAVR SRRDFGLDCD EHSTESRCCR YPLTVDFEAF GWDWIIAPKR YKANYCSGEC EFVFLQKYPH THLVHQANPR GSAGPCCTPT KMSPINMLYF NGKEQIIYGK IPAMVVDRCG CS
• Tag: His-tag
• Concentration: lot specific
• Purity: >95% pure.
• Presentation: Purified
• Buffer: Presentation State: Purified
  State: Lyophilized (0.4 µm filtered) purified protein.
  Buffer System: 0.05 M Acetate buffer, pH 4.5
• Reconstitution: Restore with 0.1M Acetate buffer pH 4.5.
• Preparation: Lyophilized (0.4 µm filtered) purified protein.
• Applications: ELISA.
  Western Blot.
• Protein Description: N-terminal His-tag including the spacer 43AA (highlighted). The AA sequence of the human myostatin part of the fusion protein.
• Note: Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
• Storage: Store lyophilized (preferably in a desiccator) at -20°C and in aliquots at -80°C.
  Reconstituted antibody can be stored at 4°C for a limited period of time; it does not show decline in activity after two weeks at 4°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_005250
• Locus ID: 2660
• UniProt ID: O14793, Q53S46
• Cytogenetics: 2q32.2
• Synonyms: GDF8; MSLHP
• Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]
• Protein Families: Druggable Genome, Secreted Protein