Interleukin-16 / IL16 (502-631, His-tag)

USD 1,105.00


Availability*
2 Weeks

Size
    • 250 ug


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Specifications

Product Data
Species Human
Expression Host E. coli
Tag His-tag
Predicted MW 13.3 kDa
Concentration 0.5 mg/ml (determined by Bradford assay)
Purity > 90 % by SDS - PAGE
Buffer Phosphate buffered saline (pH7.4).
Preparation Liquid purified protein
Reference Data
RefSeq NP_001165599
Locus ID 3603
Cytogenetics 15q25.1
Synonyms LCF; NIL16; prIL-16; PRIL16
Summary The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Protein Families Druggable Genome, Secreted Protein

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68 Mouse Clones